A man was arrested at the scene on the Ballysillan Road.
The crash involved three cars and a truck.
Police said one of the vehicles may have been stolen.
Police Ombudsman investigators are also at the scene.
The Ballysillan Road between Bilston Road and Oldpark Road has been closed in both directions.
The Ambulance Service attended the scene following reports of a crash involving a pedestrian at 10.55 am this morning.
North Belfast DUP MLA William Humphrey attended the scene and said a car had been driven at “high speed” through the area.