The burglary happened in the Skegoniell Avenue area sometime between 6.30pm and 6.50pm on Sunday.
One of the men sat with the woman while the others searched the house.
The woman was not physically injured as a result of the incident but was left shocked. It is not yet clear if any property was stolen.
Detective Sergeant Michael Hawthorne appealed for anybody who may have noticed any suspicious activity in the area or who has any information to contact detectives at Reactive and Organised Crime in Musgrave on the non-emergency number 101.
Or information can be passed to Crimestoppers anonymously on 0800 555 111.