The driver of had to received hospital treatment for facial injuries sustained in the incident which occurred at De Burgh Terrace in Derry shortly after 10.00 am on Sunday morning.
He was assaulted after he was approached by two men who drove off in his Peugeot Partner van.
The vehicle was set on fire after it was involved in a collision at Groarty Road a short time later.
Two men, both aged 20, were arrested and both are in custody assisting police with their enquiries.
The driver of the van was taken to Altnagelvin Hospital for treatment to a suspected broken cheek bone.
Police have appealed for anyone with information to contact them.
A PSNI spokesperson asked anyone who witnessed the incidents or anyone with any information to contact CID at Strand Road Police Station on 0845 600 8000.
Or, if someone would prefer to provide information without giving their details they could contact the Independent charity Crimestoppers and speak to them anonymously on 0800 555 111.